Opportunity Information: Apply for PA 18 945
Applying a Biopsychosocial Perspective to Self-Management of Chronic Pain (R01 Clinical Trial Optional) is a National Institutes of Health (NIH) discretionary grant opportunity that invites research proposals focused on improving how people manage chronic pain by explicitly using a biopsychosocial framework. In practical terms, the opportunity is aimed at studies that treat chronic pain as more than a purely biological problem and instead examine the combined influence of biological mechanisms, psychological factors (such as mood, coping, cognition, and behavior), and social or environmental conditions (such as family and community context, access to care, work demands, culture, and stigma). The core emphasis is on self-management, meaning interventions, strategies, tools, or programs that help individuals actively manage pain and its impacts in daily life rather than relying solely on clinician-delivered treatments.
The funding mechanism is the NIH R01, which is a standard research project grant designed to support well-developed, hypothesis-driven or theory-driven research projects. The notice is labeled "Clinical Trial Optional," indicating that applicants may propose a clinical trial if it fits their aims, but a clinical trial is not required; strong non-trial mechanistic, observational, or intervention-development work may also be responsive depending on how it advances biopsychosocial approaches to self-management. The announcement is associated with CFDA numbers 93.213, 93.361, and 93.393, reflecting alignment with NIH program areas tied to pain research and related health domains.
Eligibility is broad and includes many types of domestic U.S. entities such as state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; tribal organizations that are not federally recognized governments; nonprofits with and without 501(c)(3) status (excluding higher education institutions when specified); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights additional eligible applicants, signaling an intent to encourage participation from diverse institution types and communities, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). This breadth supports research that can be conducted in many settings and populations, including underrepresented or underserved communities.
Key administrative details from the source include the Funding Opportunity Number PA-18-945, creation date October 1, 2018, and an original closing date of January 7, 2022. The award ceiling and expected number of awards are not specified in the provided data, which often means applicants should consult the full announcement and NIH budget guidance for project-appropriate limits, allowable costs, and institute-specific considerations. Overall, the opportunity is best understood as a call for rigorous research that advances chronic pain self-management by integrating biological, psychological, and social dimensions, with flexibility in whether the approach involves a clinical trial.Apply for PA 18 945
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Applying a Biopsychosocial Perspective to Self-Management of Chronic Pain (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.361, 93.393.
- This funding opportunity was created on 2018-10-01.
- Applicants must submit their applications by 2022-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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