Opportunity Information: Apply for CDC RFA GH 23 0044
The Centers for Disease Control and Prevention (CDC), under the Department of Health and Human Services, announced a cooperative agreement funding opportunity under PEPFAR titled "Strengthening Regional, National, and Subnational Institutional Capacities to Sustainably Combat HIV/AIDS and Tuberculosis." The core purpose is to help host country governments and local non-governmental organizations build durable institutional strength so they can plan, manage, and monitor effective HIV and TB responses over the long term, including other related public health priorities. This is framed around the reality that many countries are moving closer to HIV epidemic control, so the next challenge is not only achieving targets but sustaining low HIV incidence and ensuring programs can run reliably under local leadership with strong systems, oversight, and accountability.
Funding is structured a bit differently than many grants. For Fiscal Year 1, CDC anticipates about $20,000,000 total available across awards, depending on the availability of funds, and expects to make about four awards. Even though the total pot is $20 million, applicants are instructed not to apply for the full amount. Instead, proposals should be built around the approximate average one-year award amount of $5,000,000. In other words, applicants should design a one-year budget of up to $5 million and propose activities that can be implemented within that scale. The published "award ceiling" for Year 1 is listed as $0, which in practice signals that the ceiling is not being set as a fixed number in the notice, and that final award sizes will be determined at the time of award rather than capped by a stated maximum.
Programmatically, applicants are expected to propose work in up to five PEPFAR-supported countries. If more than one country is included and those countries are geographically close, the application can treat them as a region and propose a regional approach rather than a set of disconnected country projects. CDC makes clear that both the final geographic scope and the exact funding level for any specific award will be decided at award time, and priorities may shift during the project period. That means applicants need to show flexibility and the ability to adapt if CDC or PEPFAR country priorities change.
The activities supported are focused on institutional capacity strengthening rather than direct service delivery alone. The notice emphasizes improving the "controls" and management backbone that keep programs effective and accountable as they transition to greater country ownership. This includes strengthening financial, operational, technical, and programmatic systems so that national and subnational institutions can reliably manage funds, oversee implementing partners, track performance, and maintain quality as external support evolves. The intent is to facilitate transition of HIV and TB programs to local oversight while maintaining results and protecting hard-won gains.
Allowable and expected activity areas are broad and systems-oriented. Examples include policy, leadership, and governance support; management, operations, and business services improvements; training and workforce development; and technical assistance across key program operations. Applicants may also propose strategic planning for sustainability, including transition planning and long-term resourcing approaches. On the measurement side, the NOFO highlights monitoring, evaluation, and performance reporting, along with community-led monitoring approaches that bring accountability closer to affected communities. It also includes finance, budgeting, and health-sector planning support for institutions, plus public health preparedness and response capabilities such as surveillance systems, laboratory capacity, health services readiness, and risk communication.
A consistent theme is that work should be designed and carried out with meaningful participation from host governments, civil society, and community representatives, explicitly including people living with HIV. These stakeholders are not meant to be consulted once and then sidelined; they are intended to be engaged throughout project development and implementation. The recipient is also expected to build in accountability measures that demonstrate respect for the rights, local knowledge, and expertise of host-country colleagues and local partners, signaling an expectation of equitable partnership and responsible collaboration rather than top-down technical control.
Administratively, this opportunity is a discretionary funding announcement using a cooperative agreement mechanism, which typically means CDC expects substantial involvement during implementation (for example, collaboration on technical direction, alignment with country plans, and coordination with PEPFAR priorities). Eligibility is listed as unrestricted, meaning applications are open to a broad range of entity types unless additional eligibility details in the full notice further clarify constraints. The opportunity number is CDC RFA GH 23 0044 under CFDA 93.067. The notice was created January 23, 2023, with an original application deadline of March 24, 2023, and electronic submissions due by 11:59 pm Eastern Time on the closing date.Apply for CDC RFA GH 23 0044
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Regional, National, and Subnational Institutional Capacities to Sustainably Combat HIV/AIDS and Tuberculosis under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Jan 23, 2023.
- Applicants must submit their applications by Mar 24, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: CDC PEPFAR Cooperative Agreement - Strengthening Institutional Capacities to Combat HIV/AIDS and Tuberculosis (CDC RFA GH 23 0044)
What is the name of this funding opportunity?
The opportunity is titled "Strengthening Regional, National, and Subnational Institutional Capacities to Sustainably Combat HIV/AIDS and Tuberculosis."
Which agency is offering this opportunity?
The funding opportunity is announced by the Centers for Disease Control and Prevention (CDC) under the Department of Health and Human Services (HHS), and it is framed under PEPFAR.
What type of funding mechanism is this?
This is a cooperative agreement. That generally means CDC expects substantial involvement during implementation, such as collaboration on technical direction, alignment with country plans, and coordination with PEPFAR priorities.
What is the core purpose of the award?
The core purpose is to help host country governments and local non-governmental organizations build durable institutional strength so they can plan, manage, and monitor effective HIV and TB responses over the long term, including other related public health priorities.
Why is CDC emphasizing institutional capacity and sustainability?
The opportunity is framed around the reality that many countries are moving closer to HIV epidemic control. The next challenge is sustaining low HIV incidence and ensuring programs can run reliably under local leadership with strong systems, oversight, and accountability.
Is this funding primarily for direct service delivery?
The notice emphasizes institutional capacity strengthening rather than direct service delivery alone. The focus is on strengthening the controls and management backbone that keep programs effective and accountable as they transition to greater country ownership.
What kinds of systems and "controls" are expected to be strengthened?
Applicants are expected to propose strengthening financial, operational, technical, and programmatic systems so institutions can reliably manage funds, oversee implementing partners, track performance, and maintain quality as external support evolves.
How much funding is anticipated for Fiscal Year 1?
For Fiscal Year 1, CDC anticipates about $20,000,000 total available across awards, depending on the availability of funds.
How many awards does CDC expect to make?
CDC expects to make about four awards.
Should applicants apply for the full $20,000,000?
No. Applicants are instructed not to apply for the full amount of the total available funding. Instead, proposals should be built around the approximate average one-year award amount of $5,000,000.
What is the recommended one-year budget size for an application?
Applicants should design a one-year budget of up to approximately $5,000,000 and propose activities that can be implemented at that scale.
Why does the Year 1 "award ceiling" appear as $0?
The published award ceiling for Year 1 is listed as $0, which in practice signals that the ceiling is not being set as a fixed number in the notice. Final award sizes will be determined at the time of award rather than capped by a stated maximum.
How many countries can be included in a proposal?
Applicants are expected to propose work in up to five PEPFAR-supported countries.
Can an application propose a regional approach rather than separate country projects?
Yes. If more than one country is included and those countries are geographically close, the application can treat them as a region and propose a regional approach rather than disconnected country projects.
Is the geographic scope guaranteed once proposed?
No. CDC states that the final geographic scope for any specific award will be decided at award time.
Can priorities change after an award is made?
Yes. The notice indicates priorities may shift during the project period, so applicants need to demonstrate flexibility and the ability to adapt if CDC or PEPFAR country priorities change.
What are examples of allowable or expected activity areas?
Examples described in the notice include policy, leadership, and governance support; management, operations, and business services improvements; training and workforce development; and technical assistance across key program operations.
Does the opportunity support sustainability and transition planning?
Yes. Applicants may propose strategic planning for sustainability, including transition planning and long-term resourcing approaches.
What does the notice say about monitoring and evaluation?
The NOFO highlights monitoring, evaluation, and performance reporting, and it also mentions community-led monitoring approaches intended to bring accountability closer to affected communities.
Are finance and budgeting activities within scope?
Yes. The notice includes finance, budgeting, and health-sector planning support for institutions as part of the expected systems-oriented work.
Does the opportunity include public health preparedness and response capacity?
Yes. The notice includes public health preparedness and response capabilities such as surveillance systems, laboratory capacity, health services readiness, and risk communication.
Who is expected to participate in project design and implementation?
The work is expected to be designed and carried out with meaningful participation from host governments, civil society, and community representatives, explicitly including people living with HIV.
Is stakeholder engagement expected to be continuous or one-time?
The notice suggests these stakeholders are intended to be engaged throughout project development and implementation, not consulted once and then sidelined.
What does CDC communicate about accountability and partnership style?
The recipient is expected to build in accountability measures that demonstrate respect for the rights, local knowledge, and expertise of host-country colleagues and local partners, reflecting an expectation of equitable partnership and responsible collaboration rather than top-down technical control.
What is the eligibility for this opportunity?
Eligibility is listed as unrestricted, meaning it is open to a broad range of entity types unless additional eligibility details in the full notice further clarify constraints.
What is the opportunity number and CFDA listing?
The opportunity number is CDC RFA GH 23 0044, under CFDA 93.067.
When was the notice created?
The notice was created on January 23, 2023.
What was the original application deadline?
The original application deadline was March 24, 2023.
What time were electronic submissions due on the closing date?
Electronic submissions were due by 11:59 pm Eastern Time on the closing date.
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