Opportunity Information: Apply for CDC RFA PS 24 0047

The Centers for Disease Control and Prevention (CDC), through NCHHSTP, is offering a cooperative agreement funding opportunity titled "High-Impact HIV Prevention and Surveillance Programs for Health Departments" (Opportunity Number CDC RFA PS 24 0047; CFDA 93.940). The intent is to help jurisdictions run an integrated, end-to-end HIV prevention and surveillance program that both prevents new HIV infections and improves health outcomes for people already living with HIV. Rather than prescribing a single rigid model, the program is designed to let each funded health department build a package of activities that fits local conditions, existing infrastructure, and epidemiologic need, while still holding applicants to clear public health priorities and measurable goals.

A central theme of the NOFO is alignment with CDC's Division of HIV Prevention strategic focus areas, particularly deeper community engagement, explicit attention to health equity, and the use of syndemic and whole-person approaches. In practical terms, that means the funded work is expected to account for overlapping health and social challenges that increase HIV vulnerability or make care harder to access, and to actively involve communities most affected by HIV in planning and implementation. The NOFO also emphasizes directing resources toward places with the highest HIV burden and the greatest unmet need, so the flexibility offered to applicants is paired with an expectation that jurisdictions will use data to justify where and how they focus services.

The funding priorities listed in the announcement track the major steps in the HIV prevention and care continuum. Applicants are expected to strengthen efforts that increase knowledge of HIV status (for example, improving and targeting testing and re-testing approaches), reduce HIV transmission and prevent new infections (including prevention strategies appropriate to local needs), and improve linkage to HIV medical care and viral suppression outcomes for people with HIV. Another explicit priority is maintaining the elimination of perinatal HIV transmission, reinforcing that pregnancy-related screening, linkage, and prevention pathways remain a core responsibility even in jurisdictions where perinatal transmission is already rare.

Surveillance and data use are not treated as separate from prevention; they are positioned as the operational backbone for public health action. The NOFO seeks accurate, complete, and timely surveillance and program data that can guide decision-making, track outcomes, and help jurisdictions respond quickly to emerging problems. A specific emphasis is placed on strengthening cluster and outbreak response, meaning the ability to detect and respond to rapid transmission networks using surveillance insights, and then to connect affected people and their networks to testing, prevention services, and care in a coordinated way. The goal is not just to collect data, but to improve the speed and effectiveness of services when indicators suggest transmission is accelerating in a community or network.

The announcement also notes that optional activities may be supported if funds are available, including additional surveillance, prevention enhancements, demonstration projects, and data modernization initiatives. This is meant to help jurisdictions evolve their systems, such as upgrading data infrastructure or piloting approaches that could later be scaled if successful. Importantly, the NOFO highlights integration of multiple funding streams: core prevention funding, surveillance funding, and Ending the HIV Epidemic (EHE) resources. This integrated structure is intended to help jurisdictions align dollars with local geographic burden, reduce fragmentation between program areas, and maximize the overall impact of federal HIV prevention investments while improving the collection and practical use of HIV data.

Eligible applicants are governmental health authorities, including state governments, county governments, city or township governments, and special district governments. The CDC anticipates making about 60 awards, and the mechanism is a cooperative agreement, which typically indicates substantial federal involvement through technical assistance, collaboration, and shared expectations around implementation and performance. The original application closing date listed is April 29, 2024. The award ceiling is shown as 0, which generally signals that applicants should rely on the NOFO's detailed funding tables and jurisdiction-specific allocations or guidance rather than a single universal maximum amount.

Finally, the NOFO allows a fiduciary entity to apply on behalf of a health department jurisdiction when appropriate. To do so, the fiduciary or bona fide agent is expected to provide a letter or memorandum of agreement (MOA) with the health department showing that it is authorized to request and manage the funds for that jurisdiction. If the MOA is not provided, the CDC indicates it may consider an alternative funding agreement to ensure that HIV prevention funds can still be provided for that health department jurisdiction. This provision is designed to reduce administrative barriers and ensure that high-burden jurisdictions are not left out due to local fiscal or contracting constraints.

  • The Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "High-Impact HIV Prevention and Surveillance Programs for Health Departments" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.940.
  • This funding opportunity was created on 2024-02-09.
  • Applicants must submit their applications by 2024-04-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 60 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments.
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